Author

Federica Monaco

Cardiff University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Simon A. JonesiD· 4 shared Aisling S. Morrin· 3 shared Ana Cardus FiguerasiD· 3 shared Carol GuyiD· 3 shared Ernest H ChoyiD· 3 shared Gareth Wyn JonesiD· 3 shared Alicia Derrac SoriaiD· 2 shared Barbara SzomolayiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

Simon A. JonesORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Pentose Phosphate Pathway Regulates Myelo-Lymphoid Lineage Specification

Jason Cosgrove, Alessandro Donada, Anne-Marie Lyne, Noémie Karabacz, Ildefonso Rodríguez‐Ramiro, Adil Midoun, Vincent Cabeli, Cécile Conrad, Gregoire Jouault, Adeline Durand, Sabrina Tenreira Bento, Emilie Tubeuf, Helen Demollin, Erica Russo, Fanny Tabarin, , Leïla Perié

This study identifies the pentose phosphate pathway's role in regulating myeloid versus lymphoid lineage specification in hematopoietic stem and progenitor cells through metabolic state-fate mapping.

bioRxiv · Sep 10, 2026 · PreprintImmunology

The Coronavirus Envelope Is Modulated by Host Inflammation and Enriched in Bioactive Lipids Required for Replication

Victoria J. Tyrrell, Ανδρέας Ζαραγκούλιας, Wendy Powell, Miran Elfar, Valeria C. Grossoni, Federica Monaco, Majd B. Protty, Ewen Stenhouse, James Heyman, Daniela Sofia Albino Costa, Lisa M. Roche, Ceri-Ann Brigid Lynch, Peter Ghazal, Simon A. Jones, Gerard J. Lambeau, , Valerie B. O’Donnell

This study characterizes the lipid composition of SARS-CoV-2 envelopes from cultured strains and patient isolates, showing inflammation-induced changes and identifying lipid targets for antiviral and antithrombotic strategies.

bioRxiv · Nov 3, 2025 · PreprintImmunology

Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis

Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes, Reuben N. Scott, Ana Cardus Figueras, Sandra Dimonte, Daniela O. Costa, Ngoc‐Nga Vinh, Federica Monaco, Robert L. Jenkins, Xiao Liu, Myles Lewis, Jason P. Twohig, Carol Guy, Aisling S. Morrin, , Simon A. Jones

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

bioRxiv · Nov 1, 2025 · PreprintPathology

Interleukin-6 elevates thrombosis via pro-coagulant phospholipids from platelet 12-lipoxygenase in rheumatoid arthritis.

Daniela O. Costa, Stuart T.O Hughes, Robert L. Jenkins, Ana Cardus Figueras, Majd B. Protty, Victoria J. Tyrrell, Ali A Hajeyah, Gareth Wyn Jones, James J Burston, Beth Morgan, Federica Monaco, David Gregory Hill, Aisling S. Morrin, Carol Guy, Alice Bacon, , Valerie B. O’Donnell

This study identifies IL-6's role in elevating thrombosis in RA via platelet 12-lipoxygenase-generated pro-coagulant phospholipids.

bioRxiv · Mar 26, 2025 · PreprintPharmacology & Toxicology

IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.

Alicia Derrac Soria, Myles Lewis, Xiao Liu, Jason P. Twohig, Federica Monaco, Sandra Dimonte, Ana Cardus Figueras, Aisling S. Morrin, Carol Guy, Benjamin C. Cossins, Robert A. Benson, Robert Andrews, Barbara Szomolay, Ernest H Choy, Paul Garside, , Simon A. Jones

The paper identifies CRTAM-expressing CD4+ T-cells in lymphoid-driven synovitis and shows that IL-6 and IL-27 inhibit their activation through STAT3 and ZEB1.

bioRxiv · Sep 3, 2024 · PreprintImmunology