Claire E. O’Leary

This study identifies RasGRP1 as a regulator of tuft cell differentiation in the intestine, showing it restricts progenitor proliferation and enhances IL-13-driven responses.

This study shows that IL-25 induces memory ILC2s in the small intestine that provide long-term protection against barrier pathogens.

This study shows Akt2 deficiency impairs Th17 differentiation, enhances Th2 differentiation, and reduces peripheral immune responses to immunization.