Keratinocyte FABP5 mediates saturated fat-induced MAPK/CCL20 signaling in psoriatic inflammation
Jianyu Yu, Jiaqing Hao, Anthony M. Avellino, Xingshan Jiang, Xiaochun Han, Ali Jabbari, Bing Li
bioRxiv · Oct 14, 2026 · PreprintImmunology
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University of IowaORCID 0000-0001-9072-9660Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Jianyu Yu, Jiaqing Hao, Anthony M. Avellino, Xingshan Jiang, Xiaochun Han, Ali Jabbari, Bing Li
bioRxiv · Oct 14, 2026 · PreprintImmunology
Jianyu Yu, Jonathan S. Shilyansky, Jiaqing Hao, Anthony M. Avellino, Yanwen Sun, Xingshan Jiang, Zhaohua Wang, Xiaochun Han, Melissa A. Curry, Sonia L. Sugg, Bing Li
This study identifies a FABP4-PD-L1 axis linking lipid metabolism to immune suppression in macrophages, showing FABP4 enables PD-L1 stabilization and correlates with obesity and breast cancer.
bioRxiv · Apr 13, 2026 · PreprintImmunology
Xingshan Jiang, Anthony M. Avellino, Jianyu Yu, Shanshan Liu, Zhaohua Wang, Xiaochun Han, Himani Thakkar, Jonathan S. Shilyansky, Zhen Xu, Nicholas Schnicker, Bhagirath Chaurasia, Jiaqing Hao, Sonia L. Sugg, Bing Li
This study identifies circulating FABP4 as a mediator of adipocyte-hepatocyte lipid crosstalk in obesity and shows that targeting it with a monoclonal antibody reduces hepatic steatosis in mouse models.
bioRxiv · Jan 26, 2026 · PreprintPathology