Bing Li

This study identifies a FABP4-PD-L1 axis linking lipid metabolism to immune suppression in macrophages, showing FABP4 enables PD-L1 stabilization and correlates with obesity and breast cancer.

This study identifies circulating FABP4 as a mediator of adipocyte-hepatocyte lipid crosstalk in obesity and shows that targeting it with a monoclonal antibody reduces hepatic steatosis in mouse models.

The paper shows that T-cell activation is initiated by partial CD45 exclusion at sub-micron contacts, leading to strong activation and cytotoxicity through small signaling changes.

This study examines FABP4 and FABP5 expression in breast cancer tissues, finding distinct roles in tumor progression and suggesting their potential as prognostic markers and therapeutic targets.

This study shows that FABP4 in tumor-associated macrophages promotes breast cancer metastasis by mediating lipid accumulation and lipolysis in response to unsaturated fatty acids.