Xiaochun Han

This study identifies a FABP4-PD-L1 axis linking lipid metabolism to immune suppression in macrophages, showing FABP4 enables PD-L1 stabilization and correlates with obesity and breast cancer.

This study identifies circulating FABP4 as a mediator of adipocyte-hepatocyte lipid crosstalk in obesity and shows that targeting it with a monoclonal antibody reduces hepatic steatosis in mouse models.

This study shows that saturated fats drive psoriasis via FABP5-mediated IL-1β/IL-17 signaling in skin macrophages, exacerbating obesity-associated psoriasis.

This study examines FABP4 and FABP5 expression in breast cancer tissues, finding distinct roles in tumor progression and suggesting their potential as prognostic markers and therapeutic targets.