Lélia Delamarre

The paper identifies coordinated neoantigen-specific CD8 T cell responses as key predictors of PD-(L)1 therapy efficacy in non-small cell lung cancer patients.

This study shows that repeated RNA-lipoplex vaccination sustains functional CD8 T cells in tumors and improves therapeutic outcomes.

The paper investigates how immunodominance affects CD8+ T cell differentiation and hierarchy after RNA vaccination, finding that dominant responses influence subdominant ones through cross-competition.

This study identifies spatially organized cDC1-T cell clusters within tumors as critical for enhancing CTL-mediated tumor rejection through local costimulation.