Author
University of Science and Technology of ChinaORCID 0000-0001-9143-2199Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yun Liu, Hui Shen, Jinzhou Li…·Fazhi Yu
This study shows that Survivin inhibition increases PD-L1 expression via cGAS stabilization, leading to immune evasion and reduced antitumor immunity.
Kaitlin Rhee, Lawrence Shue, Akimasa Adachi…·Xin X. Zhou
This paper introduces GTACs, bispecific antibodies that selectively downregulate GPCRs via endocytosis and lysosomal degradation, showing high potency and selectivity for therapeutic targets.
Fazhi Yu, Qin Zhou, Tong Zhou…·Zhenye Yang
This study identifies NOTCH2-JAG1 juxtacrine signaling as a target to reverse macrophage-mediated taxane resistance in ovarian cancer by sensitizing tumors to paclitaxel.