Author

Weiqiang Yu

Chinese Academy of SciencesORCID 0000-0002-8652-7377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aoxing ChengiD· 2 shared Fazhi YuiD· 2 shared Zhenye YangiD· 2 shared Hanyuan LiuiD· 1 shared Hui Shen· 1 shared Jing Guo· 1 shared Jing Song GuoiD· 1 shared Jinzhou Li· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Aoxing ChengORCID

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2 papers

Recent·Most cited

Survivin inhibition induces PD-L1 expression through cGAS stabilization and attenuates antitumor immunity

Yun Liu, Hui Shen, Jinzhou Li, Weiqiang Yu, Tingting Yin, Xiaodong Yuan, Wenwu Luo, Yan Li, Xue Peng, Aoxing Cheng, Jing Guo, Zhenye Yang, Fazhi Yu

This study shows that Survivin inhibition increases PD-L1 expression via cGAS stabilization, leading to immune evasion and reduced antitumor immunity.

bioRxiv · May 1, 2026 · PreprintCancer Biology

Targeting NOTCH2-JAG1 juxtacrine signaling reverses macrophage-mediated tumor resistance to taxol

Fazhi Yu, Qin Zhou, Tong Zhou, Yijia Xie, Peng Zhang, Wei He, Weiqiang Yu, Aoxing Cheng, Hanyuan Liu, Qingfa Wu, Xiaopeng Ma, Jing Song Guo, Ying Zhou, Jue Shi, Zhenye Yang

This study identifies NOTCH2-JAG1 juxtacrine signaling as a target to reverse macrophage-mediated taxane resistance in ovarian cancer by sensitizing tumors to paclitaxel.

bioRxiv · Jul 8, 2024 · PreprintCancer Biology