Joanna W. Pylvänäinen

This study identifies two distinct mechanisms by which pancreatic cancer cells extravasate: protrusion-driven invasion and endothelial retraction, with implications for anti-metastatic strategies.

This study shows SHANK3 regulates endothelial cell motility and tissue mechanics, affecting vascular development in zebrafish and mice.

This study uses fast label-free live imaging and deep learning to analyze cancer cell arrest on endothelial monolayers, finding CD44-HA interactions and flow dynamics are key factors.

The paper identifies CCT8 as a MYO10 interactor critical for filopodia functions through proteomics and functional studies in cancer cells.

CellTracksColab is a platform for compiling, analyzing, and exploring tracking data from biological movies, enabling holistic dataset analysis and identification of behavioral patterns.

Fast4DReg corrects drift in 3D microscopy datasets using 2D cross-correlations, outperforming existing tools in speed and accuracy.

Rewritten Fiji plugin TrackMate now uses StarDist, ilastik, Weka, MorphoLibJ or imported label images as detectors, stores 2D object contours, and tracks shape and intensity over time.