Yan Hao

This study identifies APR9 and KinesinA as essential components of the apical polar ring in Toxoplasma gondii, showing that their combined loss paralyzes the parasite and impairs key life cycle processes.

The paper shows that increasing translation initiation rates accelerates nucleation of aggregating proteins at polysomes, suggesting cotranslational nucleation influences proteome evolution.

The paper introduces SCAP, a method combining affinity purification, live cell imaging, and cross-linking mass spectrometry to build integrative structural models of protein complexes.

The paper investigates how paralog switching affects Sin3 complex interaction networks in humans, revealing shared and distinct interactions between SIN3A and SIN3B.