The paper uses proximity labeling to identify proteins interacting with synaptonemal complex components in Drosophila melanogaster females and finds that Cpsf5 is required for proper SC formation.

bioRxiv · Oct 14, 2025 · PreprintGenetics

Driving Integrative Structural Modeling with Serial Capture Affinity Purification

Xingyu Liu, Ying Zhang, Zhihui Wen, Yan Hao, Charles A.S. Banks, Jeffrey J. Lange, Brian D. Slaughter, Jay R. Unruh, Laurence A. Florens, Susan M. Abmayr, Jerry L. Workman, Michael P. Washburn

The paper introduces SCAP, a method combining affinity purification, live cell imaging, and cross-linking mass spectrometry to build integrative structural models of protein complexes.

Proceedings of the National Academy of Sciences · Nov 30, 2020Peer-reviewedSystems Biology

Differential complex formation via paralogs in the human Sin3 protein interaction network.

Mark K. Adams, Charles A.S. Banks, Janet L. Thornton, Cassandra G. Kempf, Ying Zhang, Sayem Miah, Yan Hao, Mihaela E. Sardiu, Maxime Killer, Gaye L. Hattem, Alexis Murray, Maria L. Katt, Laurence A. Florens, Michael P. Washburn

The paper investigates how paralog switching affects Sin3 complex interaction networks in humans, revealing shared and distinct interactions between SIN3A and SIN3B.

Molecular & Cellular Proteomics · May 28, 2020Peer-reviewedSystems Biology