Angela R. Shih

Hepatic CD8+TOX+ T-cells are a hallmark of autoimmune hepatitis

This study identifies CD8+TOX+ T-cells as a specific marker for autoimmune hepatitis using single-nucleus RNA sequencing.

Modeling development of tertiary lymphoid structures in pulmonary tuberculosis by 3D profiling and trajectory analysis

This study uses 3D reconstruction and optimal transport modeling to analyze TLS development in TB-infected lungs, revealing distinct maturation trajectories and spatial dynamics.

Single-cell transcriptomics reveals the impact of sex and age in the healthy human liver

This study uses single-cell RNA sequencing to analyze how sex and age affect gene expression and cellular interactions in healthy human liver cells.

Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas.

This study identifies suppressive myeloid cell populations in human TB granulomas using spatial transcriptomics and single-cell immunophenotyping, revealing IDO1+ dendritic cells as key regulators of immune suppression.

Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

The paper uses spatial transcriptomics to map cell types and their spatial organization in healthy and fibrotic human liver, identifying changes in hepatocyte populations during fibrosis.