Beth Eyre

Characterizing vascular function in mouse models of Alzheimer's disease, atherosclerosis, and mixed Alzheimer's and atherosclerosis

This study examines vascular function and cognitive performance in mouse models of Alzheimer's disease, atherosclerosis, and their combination, finding hemodynamic deficits in atherosclerosis mice and no differences in amyloid or plaque burden in mixed disease models.

Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins

The paper examines locomotion-induced hemodynamic responses in different vascular compartments of the whisker barrel cortex in mice, finding an early HbT decrease in draining and meningeal veins.

Bidirectional alterations in brain temperature profoundly modulate spatiotemporal neurovascular responses in-vivo: Implications for theragnostics

This study shows that changes in cortical temperature modulate neurovascular coupling, with low temperatures reducing oxygen delivery and high temperatures causing vascular oscillations.

The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice

This study shows that locomotion during awake imaging alters sensory-evoked haemodynamic responses in mice, emphasizing the need to monitor movement to avoid confounding results.

Assessment of Neurovascular Coupling & Cortical Spreading Depression in Mixed Models of Atherosclerosis & Alzheimer's Disease

This study assesses neurovascular coupling and cortical spreading depression in models of atherosclerosis and Alzheimer's disease, finding exacerbated neurovascular decline and increased amyloid-beta plaques in comorbid conditions.