Paul Roy Heath

This study assesses neurovascular coupling and cortical spreading depression in models of atherosclerosis and Alzheimer's disease, finding exacerbated neurovascular decline and increased amyloid-beta plaques in comorbid conditions.

This study shows that inhibiting SRSF1-dependent nuclear export of C9ORF72-repeat transcripts in ALS models protects neurons and identifies key RNA changes involved in disease.

This study shows that experimental atherosclerosis in mice leads to reduced cortical hemodynamics and neural activity, associated with neuroinflammation and neuronal loss.

This study examines recognition memory and glial pathology in hAPP-J20 mice, finding early memory impairment precedes Aβ deposition and glial activation.

This study identifies that human axial progenitors generate trunk neural crest cells and defines their molecular signatures.