Author

Hongyi Zhou

Altos LabsPrimary ORCID profile (0000-0002-6617-8237 · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Hongyi ZhouiD4 papers · Georgia Institute of Technology

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adam S. FrostiD· 2 shared Christopher P. ArthuriD· 2 shared D. John LeeiD· 2 shared Mauro Costa‐MattioliiD· 2 shared Peter WalteriD· 2 shared Ping ZhuiD· 2 shared Tristan Ian CrolliD· 2 shared Udit DalwadiiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Adam S. FrostORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stereoselective methyl-swapping demonstrates target specificity of cognitive enhancer

Morgane Boone, Udit Dalwadi, Aniliese Deal, Ping Zhu, Tristan Ian Croll, Maya Yamazaki, Kimberly Prescott, Renato Minopoli, Isabella Biscocho, Junhua Wang, D. John Lee, Christopher P. Arthur, Thomas G. Laughlin, Hongyi Zhou, Matthew T. Klope, , Peter Walter

The paper demonstrates that a modified ISRIB analog selectively targets a mutant eIF2B, improving synaptic plasticity and memory in mice, confirming its on-target mechanism.

bioRxiv · Feb 7, 2026 · PreprintBiochemistry

Neddylation Regulates Mitochondrial Dynamics and Turnover in the Adult Heart

Jianqiu Zou, Wenjuan Wang, Qu Chen, Lingxian Zhang, Josué Zambrano-Carrasco, Yilang Li, Yi Lu, Hongyi Zhou, Kunzhe Dong, Tohru Fukai, Masuko Ushio‐Fukai, Dawn E. Bowles, Michelle Mendiola, Ryan Gross, Weiqin Chen, , Huabo Su

This study shows that neddylation regulates mitochondrial dynamics and turnover in the adult heart, linking its disruption to cardiomyopathy and heart failure.

bioRxiv · Dec 7, 2025 · PreprintPhysiology

Harnessing the Evolution of Proteostasis Networks to Reverse Cognitive Dysfunction

Lucas Charles Reineke, Ping Zhu, Udit Dalwadi, Sean W. Dooling, Yuwei Liu, I-Ching Wang, Sara K. Young, James T. Okoh, Santosh Kumar Kuncha, Hongyi Zhou, Akshara Kannan, Hyekyung Park, Nicolas A. DeBeaubien, Tristan Ian Croll, D. John Lee, , Mauro Costa‐Mattioli

This study investigates how a genetic variant disrupts proteostasis networks, leading to cognitive dysfunction, and identifies a viral protein that can reverse these deficits.

bioRxiv · Feb 28, 2025 · PreprintNeuroscience