Author

Rajika Arora

ETH ZurichORCID 0000-0001-9396-3671Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Constance CiaudoiD· 2 shared Harry Wischnewski· 2 shared Adriano BiasiniiD· 1 shared Ana Claudia MarquesiD· 1 shared Baroj AbdulkarimiD· 1 shared Christine von Schroetter· 1 shared Fionna E. LoughliniD· 1 shared Frédéric H.‐T. AllainiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Constance CiaudoORCID

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2 papers

Recent·Most cited

The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA regulation

Małgorzata Duszczyk, Harry Wischnewski, Tamara Kazeeva, Rajika Arora, Fionna E. Loughlin, Christine von Schroetter, Ugo Pradère, Jonathan Hall, Constance Ciaudo, Frédéric H.‐T. Allain

This study determines the solution structure of DND1 bound to AU-rich RNA, revealing a novel tandem RRM-RNA recognition mechanism essential for mRNA regulation.

Nature Communications · Oct 6, 2022Peer-reviewedMolecular Biology

Translation is required for miRNA-dependent decay of endogenous transcripts.

Adriano Biasini, Baroj Abdulkarim, Stefano de Pretis, Jennifer Y. Tan, Rajika Arora, Harry Wischnewski, René Dreos, Mattia Pelizzola, Constance Ciaudo, Ana Claudia Marques

The paper shows that translation is required for miRNA-dependent transcript decay, as non-translated lncRNAs are minimally affected by miRNA loss, while translated transcripts are destabilized.

The EMBO Journal · Dec 10, 2020Peer-reviewedGenomics