Author
Centre for Addiction and Mental HealthORCID 0000-0001-9493-7918Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jonas Rybnicek, Yuxiao Chen, Milos S. Milic…·Evelyn K. Lambe
The paper investigates CHRNA5's role in amyloid pathology in aging and Alzheimer's by analyzing genetic variants and cell-type expression in human brain tissue.
Micaela Elisa Consens, Yuxiao Chen, Vilas Menon…·Daniel Felsky
The paper identifies somatostatin and intra-telencephalic neurons as significantly associated with Alzheimer's disease using bulk and single-nucleus transcriptomics across multiple datasets.
Ethan Hyungkeun Kim, Derek Howard, Yuxiao Chen…·Leon French
LaminaRGeneVis visualizes gene expression across human neocortex layers using harmonized bulk, single-nucleus, and spatial RNA sequencing data.
Yuxiao Chen, Marija Milenkovic, Wendy Horsfall…·Amy J. Ramsey
This study shows that restoring WAVE-1 in GluN1 knockdown mice rescues striatal spine density and improves maze exploration behavior.
Catharine A. Mielnik, Mary A. Binko, Yuxiao Chen…·Amy J. Ramsey
This study shows that restoring NMDAR function in adult mice with congenital NMDAR deficiency improves cognitive behaviors, suggesting potential for adult treatment of related disorders.