Author

Wendy Horsfall

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:electronic health records· 1

Frequent Co-Authors

Ali SalahpouriD· 4 shared Amy J. RamseyiD· 4 shared Evelyn K. LambeiD· 3 shared Graham L. CollingridgeiD· 2 shared John GeorgiouiD· 2 shared Katheron IntsoniD· 2 shared Marija Milenkovic· 2 shared Megan T. Sullivan· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersNeuroscience

Ali SalahpourORCID

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Author profile →

4 papers

Recent·Most cited

Characterization of the Grin1Q536R/+ mouse: a preclinical model for GRIN1-related neurodevelopmental disorder

Megan T. Sullivan, Yuanye Yan, Lyra Vania, Patrick Tidball, Quinn Pauli, Tatiana V. Lipina, Sridevi Venkatesan, Peter S.B. Finnie, Emily Fujiwara, Wendy Horsfall, John Georgiou, Robert Erne McCullumsmith, Evelyn K. Lambe, Robert P. Bonin, Ali Salahpour, , Amy J. Ramsey

The paper characterizes a Grin1Q536R/+ mouse model carrying a GRIN1 variant, showing age- and sex-dependent behavioral and physiological changes linked to GRIN1-NDD.

bioRxiv · Sep 15, 2026 · PreprintNeuroscience

β-hydroxybutyrate improves convulsions in mice carrying the GRIN1 Y647S/+ pathogenic variant

Megan T. Sullivan, Patrick Tidball, Yuanye Yan, Katheron Intson, Wenjuan Chen, Yuchen Xu, Sridevi Venkatesan, Wendy Horsfall, John Georgiou, Peter S.B. Finnie, Robert E. McCullumsmith, Evelyn K. Lambe, Stephen F. Traynelis, Ali Salahpour, Hongjie Yuan, , Amy J. Ramsey

This study investigates the effects of the GRIN1 Y647S variant in mice, showing that β-hydroxybutyrate reduces convulsions associated with the variant.

bioRxiv · Aug 21, 2024 · PreprintNeuroscience

Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice

Yuxiao Chen, Marija Milenkovic, Wendy Horsfall, Ali Salahpour, Scott H. Soderling, Amy J. Ramsey

This study shows that restoring WAVE-1 in GluN1 knockdown mice rescues striatal spine density and improves maze exploration behavior.

PLoS ONE · Oct 23, 2018Peer-reviewedNeuroscience

Consequences Of NMDA Receptor Deficiency Can Be Rescued In The Adult Brain

Catharine A. Mielnik, Mary A. Binko, Yuxiao Chen, Adam J. Funk, Emily M. Johansson, Katheron Intson, Nirunthan Sivananthan, Rehnuma Islam, Marija Milenkovic, Wendy Horsfall, Ruth A. Ross, Laurent Groc, Ali Salahpour, Robert Erne McCullumsmith, Shreejoy J. Tripathy, , Amy J. Ramsey

This study shows that restoring NMDAR function in adult mice with congenital NMDAR deficiency improves cognitive behaviors, suggesting potential for adult treatment of related disorders.

Molecular Psychiatry · Jan 1, 2018Peer-reviewedNeuroscience