Zhenyue Chen

SALM uses deep learning to convert motion-blurred streaks into high-resolution brain imaging, reducing reconstruction time and enabling scalable, cross-platform applications.

Event2Flow uses event-based sensors to efficiently map blood flow in mice, enabling noninvasive vascular and brain imaging with reduced data and computational demands.

The paper shows pial collaterals propagate neurovascular signals between cortical territories, synchronizing blood flow responses beyond activated areas.

This paper develops a new imaging technique to study brain perfusion in mice during ischemic stroke, showing its ability to map vascular changes and assess therapeutic effects.

Pia-FLOW maps hemodynamic properties of the murine pial vascular network and shows its unified response to arterial occlusion.

The paper visualizes alpha-synuclein inclusions and iron deposition in M83 mouse models of Parkinson's disease using in vivo imaging and ex vivo validation techniques.

This paper demonstrates non-invasive whole brain imaging of tau deposits using vMSOT and PBB5 probe in P301L mice, showing specific binding and retention in tau-laden regions.

This study uses a hybrid imaging platform to simultaneously observe hemodynamic and calcium responses in mice brains during sensory stimulation, revealing their complex interplay.

This paper characterizes CRANAD-2 for detecting amyloid-beta deposits in Alzheimer's mouse models using multi-spectral optoacoustic tomography and fluorescence imaging.

This study detects cerebral tauopathy in P301L mice using large-field multifocal illumination fluorescence microscopy and a fluorescent ligand, showing increased probe retention in affected mice.

The paper introduces vMSOT with AOI987 to quantify Aβ deposition in AD mouse models, revealing strain-specific patterns.

This paper introduces a transcranial fluorescence microscopy technique to detect amyloid-beta plaques in mouse models of Alzheimer's disease at single-plaque resolution across the entire brain.