Author

Serine Avagyan

Boston Children's HospitalORCID 0000-0001-9522-6237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Leonard Ira ZoniD· 3 shared Anne L. RobertsoniD· 2 shared Olivia Mitchell· 2 shared Song P. YangiD· 2 shared Aaron McKennaiD· 1 shared Alejo Rodriguez-FraticelliiD· 1 shared Alex Maya Pombo· 1 shared Alexander MeissneriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Leonard Ira ZonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Choline Kinase Alpha Inhibition is a Mutation Agnostic Therapeutic Vulnerability in Clonal Hematopoiesis

Brandon J.F. Gheller, Olivia Mitchell, Michael Quach…·Leonard Ira Zon

This study identifies CHKA/PAF metabolic dependency in clonal hematopoiesis across multiple mutations and shows its suppression reduces clonal expansion.

DOI 10.64898/2026.10.26.760729

zebrafishmouse

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 9, 2024

Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis

Chloé S. Baron, Olivia Mitchell, Serine Avagyan…·Leonard Ira Zon

The paper shows that leukemia cells secrete apelin, which promotes clonal expansion of niche endothelial cells and drives leukemogenesis in zebrafish.

2 citations

zebrafishexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 7, 2024

A molecular switch: Ro5-3335 drives hematopoietic stem cell division and clonality through distinct RUNX1 binding partners

Anne L. Robertson, Yue Lü, Avik Choudhuri…·Leonard Ira Zon

This study identifies Ro5-3335 as a chemical that increases HSC clone number and clonal diversity by altering RUNX1 binding partners in zebrafish and mouse models.

5 citations

zebrafishmouse

𝕏 PostBluesky