Pierre Mangin

This study shows that type III collagen fibers aligned parallel to flow support stable platelet adhesion at high shear rates, promoting thrombus formation.

This study shows that depleting all platelet integrins in mice increases bleeding time, impairs arterial thrombosis, and reduces tumor growth and metastasis.

This study identifies CD24 as a regulator of tumor cell-platelet interactions that enhance metastatic potential and suggests it as a druggable target.