Cristina Liboni

Selective targeting of RalA with intrabodies impairs Triple Negative Breast Cancer metastasis

This paper develops RalA-specific intrabodies that inhibit mitochondrial fission and extracellular vesicle secretion, reducing metastasis in a TNBC mouse model.

Depletion of all platelet integrins impacts hemostasis, thrombosis and tumor metastasis

This study shows that depleting all platelet integrins in mice increases bleeding time, impairs arterial thrombosis, and reduces tumor growth and metastasis.

Tumoral CD24 tunes platelets binding and pro-metastatic functions

This study identifies CD24 as a regulator of tumor cell-platelet interactions that enhance metastatic potential and suggests it as a druggable target.