Author

Jonny Mendoza‐Castrejon

Washington University in St. LouisORCID 0000-0001-9558-152XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Elisabeth Denby· 2 shared Emily B. Casey· 2 shared Jeffrey A. MageeiD· 2 shared Riddhi M. PateliD· 2 shared Rohini MuthukumariD· 2 shared Helen H. WangiD· 1 shared J. Michael WhiteiD· 1 shared Jihye YooniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Elisabeth Denby

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SKIDA1 transiently sustains MLL::ENL-Expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming

Jonny Mendoza‐Castrejon, Wei Yang, Elisabeth Denby, Rohini Muthukumar, Emily B. Casey, Riddhi M. Patel, Sarah Kathleen Tasian, Jeffrey A. Magee

This study identifies SKIDA1 as a gene promoting B-lineage priming in neonatal MLL::ENL-expressing hematopoietic progenitors, with implications for age-specific leukemogenesis.

Blood Neoplasia · Nov 20, 2025Peer-reviewedCancer Biology

Fetal context conveys heritable protection against MLL-rearranged leukemia that depends on MLL3

Jonny Mendoza‐Castrejon, Wei Yang, Elisabeth Denby, Helen H. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luís F.Z. Batista, Jeffrey A. Magee

The paper shows fetal exposure to MLL::ENL creates a heritable leukemia-resistant state by altering hematopoietic progenitor behavior, which can be overcome by MLL3 inactivation or cooperating mutations.

bioRxiv · Mar 11, 2025 · PreprintCancer Biology