Author

Luís F.Z. Batista

Washington University in St. LouisORCID 0000-0002-4178-0205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alexandre Teixeira VessoniiD· 1 shared Andrew P. StoneiD· 1 shared Clementine Payne· 1 shared Dong Hoon LeeiD· 1 shared Elisabeth Denby· 1 shared Emily B. Casey· 1 shared Estelle CarminitaiD· 1 shared Ethan Walsey· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandre Teixeira VessoniORCID

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3 papers

Recent·Most cited

Induction of Moderate DNA Damage Enhances Megakaryopoiesis and Platelet Production

Roelof Hendrik Bekendam, Virginia Camacho, Andrew P. Stone, María N. Barrachina, Siobhan Laken Branfield, Estelle Carminita, Isabelle C. Becker, Dong Hoon Lee, Ethan Walsey, Clementine Payne, Jakub Kaplan, Julia Tilburg, Sharmistha Pal, Luís F.Z. Batista, Joseph E. Italiano, Kellie R. Machlus

The paper shows that low-dose PARP inhibitors or gamma-irradiation increase DNA damage in megakaryocytes and their progenitors, leading to higher megakaryopoiesis and platelet production in mice.

bioRxiv · May 8, 2025 · PreprintCell Biology

Fetal context conveys heritable protection against MLL-rearranged leukemia that depends on MLL3

Jonny Mendoza‐Castrejon, Wei Yang, Elisabeth Denby, Helen H. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luís F.Z. Batista, Jeffrey A. Magee

The paper shows fetal exposure to MLL::ENL creates a heritable leukemia-resistant state by altering hematopoietic progenitor behavior, which can be overcome by MLL3 inactivation or cooperating mutations.

bioRxiv · Mar 11, 2025 · PreprintCancer Biology

Telomere dysfunction represses HNF4α leading to impaired hepatocyte development and function

Evandro Luís de Oliveira Niero, Wilson C. Fok, Alexandre Teixeira Vessoni, Kirsten Ann Brenner, Luís F.Z. Batista

This study shows that telomere dysfunction reduces HNF4α, impairing hepatocyte development and function in human cells, and identifies potential therapeutic strategies.

bioRxiv · Apr 25, 2019 · PreprintDevelopmental Biology