Author

Emily B. Casey

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Elisabeth Denby· 3 shared Jeffrey A. MageeiD· 3 shared Riddhi M. PateliD· 3 shared Rohini MuthukumariD· 3 shared Jonny Mendoza‐CastrejoniD· 2 shared Ran CheniD· 2 shared Grant Anthony ChalleniD· 1 shared Guojia XieiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

Elisabeth Denby

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Author profile →

3 papers

Recent·Most cited

MLL3 and MLL4 sustain hematopoietic stem cell multipotency by opposing a B-cell default state

Helen C. Wang, Ran Chen, Wei Yang, Rohini Muthukumar, Tingting Hu, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Run Zhang, Guojia Xie, Kai Ge, Grant Anthony Challen, Jeffrey J. Bednarski, Jeffrey A. Magee

This study shows that MLL3 and MLL4 maintain hematopoietic stem cell multipotency by opposing a B-cell default state through distinct enhancer regulation mechanisms.

Blood · May 12, 2026Peer-reviewedCell Biology

SKIDA1 transiently sustains MLL::ENL-Expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming

Jonny Mendoza‐Castrejon, Wei Yang, Elisabeth Denby, Rohini Muthukumar, Emily B. Casey, Riddhi M. Patel, Sarah Kathleen Tasian, Jeffrey A. Magee

This study identifies SKIDA1 as a gene promoting B-lineage priming in neonatal MLL::ENL-expressing hematopoietic progenitors, with implications for age-specific leukemogenesis.

Blood Neoplasia · Nov 20, 2025Peer-reviewedCancer Biology

Fetal context conveys heritable protection against MLL-rearranged leukemia that depends on MLL3

Jonny Mendoza‐Castrejon, Wei Yang, Elisabeth Denby, Helen H. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luís F.Z. Batista, Jeffrey A. Magee

The paper shows fetal exposure to MLL::ENL creates a heritable leukemia-resistant state by altering hematopoietic progenitor behavior, which can be overcome by MLL3 inactivation or cooperating mutations.

bioRxiv · Mar 11, 2025 · PreprintCancer Biology