Tariq M. Rana

This study develops a modified SARS-CoV-2 mRNA vaccine, G1-C, that enhances antibody and T cell responses and provides better in vivo protection against the virus.

This study examines the cell-type specific effects of opioid use disorder and HIV on the human brain, identifying changes in gene regulation, metabolism, and immune responses across different brain regions.

This study uses human iPSC-derived microglia and 3D cerebral assembloid models to investigate HIV and methamphetamine-induced CNS damage, revealing increased inflammation and neurotoxicity with reduced TREM2 function.

This paper identifies GBP5 as an ISG that inhibits viral replication by blocking N-glycosylation of viral proteins, including SARS-CoV-2 spike, through interaction with the OST complex.

This study shows that m6A methylation, regulated by METTL3, controls the innate immune response in β-cells during T1D onset by modulating OAS mRNA stability.

This study uses single-cell RNA sequencing to identify immune cell exhaustion in HIV-infected individuals, revealing novel T cell subclusters and potential therapeutic targets.