Russell Scott Ray

A combinatorial gene therapy targeting inflammation and chondrocyte health slows OA progression and reduces pain in murine and equine models.

This study identifies validated genetic and tracer tools to map knee-innervating neurons, aiding in understanding joint pain mechanisms.

This study identifies sensory fiber types in mouse TMJ tissues using immunohistochemistry, finding peptidergic fibers dominate with minimal non-peptidergic nociceptors.

This study shows that Vglut2-based glutamatergic signaling in central noradrenergic neurons is not required for normal breathing or chemosensory reflexes in mice.

This study shows that reprogramming mature mammalian cochlear cells with ATOH1, GFI1, and POU4F3 is hindered by epigenetic inaccessibility and cell-cell signaling, particularly Notch signaling.

The paper introduces a CRISPR toolkit for generating intersectional genetic mice to study cellular circuits, demonstrating its use in neuronal and ovarian populations.