Loo Chien Wang

This study shows that increased ovarian ECM stiffness with age impairs follicle function by reducing granulosa cell proliferation and oocyte quality through TGF-β signaling.

This paper develops an optogenetic tool to control PKC epsilon activity with spatiotemporal precision and validates its function in phosphorylation events.

This study introduces Opto-OGT, an optogenetic tool to control O-GlcNAc modification, showing its ability to modulate mTORC and AKT signaling in response to light.