Graeme F. Woodworth

This study shows that pro-inflammatory polarization of macrophages increases nuclear stiffness despite reduced lamin A/C levels, suggesting chromatin changes drive nuclear mechanics.

This study identifies the A-type lamin rod domain as the key determinant of nuclear deformability, revealing its unique role in resisting large mechanical forces on the nucleus.

This study uses machine learning to enhance focused ultrasound for BBB opening, improving nanoparticle delivery and tumor DNA detection in brain tumors.

This study demonstrates closed-loop sonothermogenetic control of CAR T cells to achieve metronomic activation in brain tumors without harming healthy tissue.