Author

Sarah J. Henretta

Cornell UniversityORCID 0000-0001-9891-3104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jan LammerdingiD· 2 shared Margaret A. Elpers· 2 shared Giuliano ScarcelliiD· 1 shared Graeme F. WoodworthiD· 1 shared Hassan SaadiiD· 1 shared Ioannis NtekasiD· 1 shared Iwijn De VlaminckiD· 1 shared Jacob D. Odell· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Jan LammerdingORCID

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2 papers

Recent·Most cited

Cell Biologynpj Biological Physics and Mechanics.Peer-reviewedJun 1, 2026

Polarization Increases Nuclear Stiffness in Macrophages Despite Reduction in Lamin A/C Levels

Margaret A. Elpers, Jacob Odell, Sarah J. Henretta…·Jan Lammerding

This study shows that pro-inflammatory polarization of macrophages increases nuclear stiffness despite reduced lamin A/C levels, suggesting chromatin changes drive nuclear mechanics.

2 citations

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 11, 2024

Nuclear envelope rupture in cardiomyocytes orchestrates early transcriptomic changes and immune activation in LMNA-related dilated cardiomyopathy that are reversed by LINC complex disruption

Noam Zuela-Sopilniak, Julien L. P. Morival, Ioannis Ntekas…·Jan Lammerding

This study identifies NE rupture in LMNA-DCM cardiomyocytes as a driver of transcriptomic changes and immune activation, which can be reversed by LINC complex disruption.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky