Author

Margaret A. Elpers

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jan LammerdingiD· 2 shared Sarah J. HenrettaiD· 2 shared Giuliano ScarcelliiD· 1 shared Graeme F. WoodworthiD· 1 shared Hassan SaadiiD· 1 shared Ioannis NtekasiD· 1 shared Iwijn De VlaminckiD· 1 shared Jacob D. Odell· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Jan LammerdingORCID

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2 papers

Recent·Most cited

Polarization Increases Nuclear Stiffness in Macrophages Despite Reduction in Lamin A/C Levels

Margaret A. Elpers, Jacob Odell, Sarah J. Henretta, Tong Shu, Yogeshwari Sanjayrao Ambekar, Hassan Saadi, Graeme F. Woodworth, Warren R. Zipfel, Giuliano Scarcelli, Liam J. Holt, Jan Lammerding

This study shows that pro-inflammatory polarization of macrophages increases nuclear stiffness despite reduced lamin A/C levels, suggesting chromatin changes drive nuclear mechanics.

npj Biological Physics and Mechanics. · Jun 1, 2026Peer-reviewedCell Biology

Nuclear envelope rupture in cardiomyocytes orchestrates early transcriptomic changes and immune activation in LMNA-related dilated cardiomyopathy that are reversed by LINC complex disruption

Noam Zuela-Sopilniak, Julien L. P. Morival, Ioannis Ntekas, Margaret A. Elpers, Rohit Agarwal, Sarah J. Henretta, Jacob D. Odell, Iwijn De Vlaminck, Jan Lammerding

This study identifies NE rupture in LMNA-DCM cardiomyocytes as a driver of transcriptomic changes and immune activation, which can be reversed by LINC complex disruption.

bioRxiv · Jun 11, 2024 · PreprintCell Biology