Thalida Em Arpawong

Form and function of actin impacts actin health and aging.

This study investigates how actin structure and function affect aging in C. elegans and finds that actin dysfunction accelerates aging hallmarks and correlates with human age-related decline in gait speed.

Nuclear Mitochondrial Interaction Test Reveals Sex-Dependent Mitochondrial SNPs Interacting with Klotho Variants on Diabetes Risk

The paper identifies mitochondrial SNPs interacting with Klotho variants to influence diabetes risk, showing sex-dependent effects using the NuMIT method.

Blood Omics Models for System-Specific Mortality Risk Estimation

The paper develops mortality-based predictors of biological age for 9 physiological systems using blood data from the UK Biobank and validates them in the Health and Retirement Study.

Genetic variation in ALDH4A1 predicts muscle health over the lifespan and across species

The paper identifies ALDH4A1 genetic variation as a biomarker for age-related muscle health across species using C. elegans and human data.