Author

Caitlin M. Lange

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0003-4146-5288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:genetic perturbation / CRISPR· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Caroline KumstaiD· 2 shared Aeowynn J. CoakleyiD· 1 shared Athena AlcalaiD· 1 shared Bérénice Anath BenayouniD· 1 shared Cheng‐Ju KuoiD· 1 shared Cristal M. HilliD· 1 shared Daniella Suh· 1 shared Darius Moaddeli· 1 shared

Activity by Year

2026-2026 · peak 2/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Caroline KumstaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 3, 2026

Hormetic heat shock activates HLH-30/TFEB independently of canonical nutrient-sensing pathways

Tatiana M. Moreno, Michelle E Brown, Caitlin M. Lange…·Caroline Kumsta

This study shows that heat shock activates HLH-30/TFEB independently of mTORC1 and AMPK, revealing stress-specific regulation of this transcription factor.

DOI 10.64898/2026.09.01.748694

C. elegansgenetic perturbation / CRISPR

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Cell BiologyiSciencePeer-reviewedAug 24, 2026

Form and function of actin impacts actin health and aging.

Maxim Averbukh, Hunter T. Nelson, Tiffany V. Wang…·Ryo Higuchi‐Sanabria

This study investigates how actin structure and function affect aging in C. elegans and finds that actin dysfunction accelerates aging hallmarks and correlates with human age-related decline in gait speed.

3 citations

C. elegansbulk RNA-seq

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