NeurosciencebioRxivPreprint
Pharmacologic Stabilization of Retromer Rescues Endosomal Pathology Induced by Defects in the Alzheimer's gene SORL1
Swati Mishra, Allison Knupp, Chizuru Kinoshita…·Jessica E. Young
The paper tests if a retromer stabilizing drug, TPT-260, can correct endosomal and Alzheimer's-related pathologies in neurons with SORL1 variants.
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