Author

Cassi M. Friday

University of KentuckyORCID 0000-0001-9712-316XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Cathryn T SmithiD· 2 shared Josh M. MorgantiiD· 2 shared Lance A. JohnsoniD· 2 shared Nicholas A. DevanneyiD· 2 shared Sangderk LeeiD· 2 shared Adeline E. WalshiD· 1 shared Amy A. Gorman· 1 shared Danielle S. Goulding· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPhysiology

Cathryn T SmithORCID

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2 papers

Recent·Most cited

PhysiologyNeurobiology of DiseasePeer-reviewedMay 30, 2025

APOE4 alters the lipid droplet proteome and modulates droplet dynamics

Cassi M. Friday, Isaiah O. Stephens, Cathryn T Smith…·Lance A. Johnson

This study shows that APOE4 increases lipid droplet accumulation and alters their composition in microglia, resembling a pro-inflammatory state, and overlaps with AD-associated proteomes.

37 citationstop 1%

mouseproteomics

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NeuroscienceCell ReportsPeer-reviewedMar 1, 2023

APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

Sangderk Lee, Nicholas A. Devanney, Lesley R. Golden…·Lance A. Johnson

This study investigates how APOE4 affects microglial immunometabolism across age, amyloid pathology, and inflammation using multi-omics approaches.

203 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky