Edward C. Emery

This study identifies GM-CSF as a key mediator of vertebral bone marrow emergency myelopoiesis in neuropathic pain, linking meningeal immunity to pain pathogenesis.

This study identifies opioid-dependent inhibition of neurotransmitter release as the primary mechanism of analgesia in NaV1.7 null mutants in mice and humans.

The paper identifies silent cold-sensing neurons that become active in neuropathic pain and contribute to cold allodynia through peripheral sensitization.

The paper shows that increased intracellular sodium inhibits fentanyl's effect on Nav1.8 currents in sensory neurons.