Pasha A. Davoudian

This study shows psilocybin selectively affects GABAergic interneurons in the mouse medial frontal cortex, reducing somatostatin-expressing and increasing parvalbumin-expressing neuron activity.

This study shows psilocybin alters large-scale cortical network connectivity in mice by strengthening inputs from perceptual and medial regions and weakening cortico-cortical loops, dependent on drug-evoked spiking activity.

The paper classifies psychedelics and psychoactive drugs using brain-wide imaging of c-Fos expression and machine learning, achieving above-chance accuracy in drug identification.

This study identifies specific pyramidal cell types and 5-HT2A receptors in the medial frontal cortex as essential for psilocybin's long-term therapeutic effects.

The paper investigates how cholinergic systems contribute to changes in brain functional connectivity during nicotine withdrawal in male mice, identifying two distinct long-range cholinergic networks and associated genes.

This study investigates the behavioral and neural effects of 5-MeO-DMT in mice, showing dose-dependent changes in behavior and long-term dendritic spine density increases without affecting spine size.

This study maps brain regions with drug-induced c-Fos expression after psilocybin and ketamine in mice, revealing shared and distinct patterns linked to glutamatergic receptors.

The paper presents a synaptic physiology dataset and analysis platform to study cortical microcircuit structure and synaptic properties in mouse and human neocortex, revealing layer-dependent connectivity and subclass-specific dynamics.

The paper links connectomic features to synaptic strengths and subcellular computations in Drosophila olfactory neurons.

This study shows psilocybin rapidly and persistently increases dendritic spine size and density in mouse frontal cortex, with lasting behavioral and neurophysiological effects.

The paper identifies a cholinergic relay mechanism in Drosophila that transforms the absence of punishment into a reward signal through dopamine neuron interactions.

The paper examines sparse excitatory connectivity in adult mouse and human cortex using electrophysiology and optogenetics, finding sparse connections and synaptic dynamics across layers.