Author

Noah Chen

Columbia UniversityORCID 0000-0001-9795-4561Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Dylan L. MariuzzaiD· 2 shared Fangda LiiD· 2 shared Kenia de los SantosiD· 2 shared Nicholas ArpaiaiD· 2 shared Tal DaninoiD· 2 shared Zaofeng YangiD· 2 shared Cathy Lee MendelsohniD· 1 shared Edward R. BallisteriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Dylan L. MariuzzaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyScience Translational MedicinePeer-reviewedSep 16, 2026

Engineered probiotics for tumor-targeted combination chemoimmunotherapy

Zaofeng Yang, Jongwon Im, Noah Chen…·Nicholas Arpaia

This paper develops a bacterial platform that combines enzyme/prodrug chemotherapy and immunotherapy to enhance antitumor responses with improved safety in a murine tumor model.

1 citation

mouseproteomics

𝕏 PostBluesky

ImmunologyScience Translational MedicinePeer-reviewedJul 22, 2026

Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy

Mathieu Rouanne, Noah Chen, Dylan L. Mariuzza…·Nicholas Arpaia

This study shows engineered E. coli expressing CXCL13 enhances bladder cancer immunotherapy when combined with PD-1 blockade by promoting tumor-specific antibody responses.

2 citations

mouseproteomics

𝕏 PostBluesky