Zaofeng Yang

This paper develops a bacterial platform that combines enzyme/prodrug chemotherapy and immunotherapy to enhance antitumor responses with improved safety in a murine tumor model.

This study shows engineered E. coli expressing CXCL13 enhances bladder cancer immunotherapy when combined with PD-1 blockade by promoting tumor-specific antibody responses.

This study shows that temperate phages enhance bacterial fitness by remodeling flagella via RNA-guided transcription factors, improving motility and immune evasion.