Yiechang Lin

The paper identifies CLCC1 as a client of Torsin ATPases, showing they organize CLCC1 to maintain ER bilayer and lipid homeostasis, with implications for MASH development.

This study evaluates AlphaFold2-Multimer and AlphaFold3's ability to predict oligomeric states of proteins, showing their utility but also highlighting limitations for proteins without structural representatives in the training set.

This study shows that TamB transfers lipids through a hydrophobic groove connecting inner and outer membranes in Gram-negative bacteria, with lipid release dependent on TamA binding.

The paper shows TMEM63 proteins function as mechanically activated lipid scramblases, modulated by cholesterol, contributing to membrane resilience.