Margo P. Emont

This study uses snRNA-seq to analyze human adipose tissue depots, identifying distinct adipocyte and progenitor subpopulations and depot-specific intercellular communication networks, with changes observed in disease states.

This study identifies rapid remodeling of human subcutaneous white adipose tissue within one month after bariatric surgery using snRNA-seq, revealing changes in adipocyte populations and transcriptional dynamics.

The paper creates a single-cell transcriptome atlas of human subcutaneous adipose tissue vascular cells, identifies sub-AdECs, and links their properties to metabolic disease.

The paper identifies obesity-related transcriptional changes in circulating extracellular vesicles and links them to adipose tissue epigenetics and inflammatory disease risk.

The paper uses single-nuclear RNA sequencing to analyze adipose tissue in lymphedema patients, identifying a stromal cell population that promotes lymphangiogenesis.

This study shows that mesothelial cells are not a source of visceral adipocytes in mice, challenging a recent paradigm based on Wt1 lineage tracing.