Kathleen C. Woulfe

This study investigates cardiac myofibril remodeling in Burmese pythons during digestion using multi-omics approaches, revealing post-translational modifications as key to increased contractility.

This study identifies a sexually dimorphic NLRP3 signaling pathway in right ventricular failure, showing estrogen receptor α mediates protection against NLRP3-induced contractile dysfunction in cardiomyocytes.

This study shows low-dose GLP-1RA therapy improves cardiac and hepatic function in HFpEF without weight loss, through mechanisms like reduced fibrosis and lipid accumulation.

This paper describes a mouse model of Laing distal myopathy caused by the R1500P mutation in {beta}-myosin, showing structural and functional muscle defects and weakened acto-myosin binding.