Author
Helmholtz Centre for Infection ResearchORCID 0000-0001-9886-9668Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Philipp Germer, Lukas Gericke, Lars-Hendrik Koeppl…·Jennifer N. Andexer
This study investigates the ability of SAM-dependent enzymes to accept D-SAM instead of L-SAM, finding that several enzymes can utilize D-SAM and highlighting implications for enzyme engineering.
Katharina G. Wandera, Stefan Schmelz, Angela Migur…·Chase L. Beisel
This paper shows AcrVIB1 inhibits CRISPR-Cas13b by promoting unproductive crRNA binding and degradation, revealing a mechanism to suppress immune defense.
Hella Schwanke, Vladimir Gonçalves Magalhães, Stefan Schmelz…·Melanie M. Brinkmann
This paper identifies M35 as a viral protein that binds DNA and inhibits IRF3-mediated gene expression, including Ifnb1, thereby suppressing the antiviral type I IFN response.