Author

Ian F. Smith

University of California, IrvineORCID 0000-0001-9910-195XUnclaimed ORCID profile · follow to get notified of new preprints

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Ian Smith1 paper

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Alberto GranzottoiD· 2 shared Amanda McQuadeiD· 2 shared Ian ParkeriD· 2 shared Jean Paul ChadarevianiD· 2 shared Mathew M. Blurton-JonesiD· 2 shared Stefano Luca SensiiD· 2 shared Amit JairamaniD· 1 shared Hansang Cho· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Alberto GranzottoORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 18, 2024

ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia

Alberto Granzotto, Amanda McQuade, Jean Paul Chadarevian…·Ian F. Smith

This study shows that ER and SOCE Ca2+ signals are not required for directed migration of human microglia in response to purinergic stimuli, suggesting a Ca2+-independent mechanism involving cyclic AMP.

2 citations

humanexperimental assay

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NeuroscienceeLifePeer-reviewedFeb 22, 2022

TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

Amit Jairaman, Amanda McQuade, Alberto Granzotto…·Michael Cahalan

This study shows that TREM2 loss in human iPSC-derived microglia leads to altered Ca2+ signaling and motility via purinergic receptor pathways.

62 citationstop 4%

humanexperimental assay

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