Kookjoo Kim

This study identifies the RY12 domain of RyR1 as an ADP sensor and reveals dantrolene's binding mechanism through cryo-EM structures.

This study uses cryo-EM and molecular dynamics to analyze conformational transitions in AE1 and shows how PIP2 lipids inhibit transport by stabilizing the outward-facing state.

This paper presents a workflow for cryo-EM structure determination of small proteins using heterogeneous ab initio reconstruction, successfully solving structures of three small proteins with resolutions below 5 Å.