Francesca Vallese

This study determines the high-resolution structures of stomatin complexes with AQP-1 and UT-B, revealing their structural basis of association and role in erythrocyte osmotic balance.

This study presents a 2.25 Å cryo-EM structure of the vault cap, revealing a 13-fold symmetric arrangement and a positively charged exterior with implications for vault function and therapeutic applications.

This study demonstrates the use of divalent nanobodies to recruit NEDD4-2 E3 ligase to degrade ion channels, reducing their function with minimal off-target effects.

The paper defines the Band 3 N-terminus interactome in red blood cells, revealing its role in hypoxic adaptation through BLVRB-dependent S-nitroso transfer and metabolic remodeling.

This study uses cryo-EM and molecular dynamics to analyze conformational transitions in AE1 and shows how PIP2 lipids inhibit transport by stabilizing the outward-facing state.

The paper investigates how G6PD variants affect red blood cell storage, transfusion performance, and recipient physiology using multiple datasets and experimental models.

The paper introduces cryoDRGN-AI, a method for ab initio 3D reconstruction of cryo-EM and cryo-ET datasets, revealing new conformational states and unresolved motions.

TARDIS is a deep learning framework that rapidly and accurately segments membranes and filaments in electron microscopy data, enabling large-scale biophysical analysis.