Author

Colin M. Crump

University of CambridgeORCID 0000-0001-9918-9998Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Henry G. BarrowiD· 3 shared Stephen C. GrahamiD· 3 shared Alex S. NicholsoniD· 2 shared Daniel A NashiD· 2 shared Janet Elwyn DeaneiD· 2 shared Viv Connor· 2 shared Anton James EnrightiD· 1 shared Harvey E. JohnstoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

Henry G. BarrowORCID

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3 papers

Recent·Most cited

MicrobiologyScience AdvancesPeer-reviewedOct 7, 2026

Herpes simplex virus pUL56 abolishes neuronal activity by removing voltage-gated ion channels from the plasma membrane

Daniel A Nash, Henry G. Barrow, Robin Antrobus…·Stephen C. Graham

This study identifies HSV-1 protein pUL56 as responsible for removing voltage-gated ion channels from neuronal plasma membranes, disrupting calcium signaling and neuronal activity.

DOI 10.1126/sciadv.aei1796

humanproteomics

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MicrobiologybioRxivPreprintAug 22, 2025

Optimisation of lytic herpes simplex virus infection in human induced pluripotent stem cell derived cortical neurones

Daniel A Nash, Alex S. Nicholson, Henry G. Barrow…·Stephen C. Graham

This study optimizes HSV-1 infection in human iPSC-derived cortical neurones, enabling efficient and synchronous infection for microscopy and biochemical analysis.

1 citation

humanproteomics

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MicrobiologyeLifePeer-reviewedFeb 24, 2025

Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

Kamal L. Nahas, Viv Connor, Kaveesha Jayani Wijesinghe…·Colin M. Crump

This study uses 3D correlative fluorescence and X-ray tomography to analyze HSV-1 mutants, revealing roles of viral proteins in morphogenesis and showing envelopment occurs via budding.

7 citations

fluorescence / live-cell microscopyimaging

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