Author

Daniel A Nash

University of CambridgeORCID 0000-0002-2004-855XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Janet Elwyn DeaneiD· 4 shared Stephen C. GrahamiD· 4 shared Alex S. NicholsoniD· 3 shared Henry G. BarrowiD· 3 shared Colin M. CrumpiD· 2 shared John SuberuiD· 2 shared Robin AntrobusiD· 2 shared Valeria LullaiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

Janet Elwyn DeaneORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Herpes simplex virus pUL56 abolishes neuronal activity by removing voltage-gated ion channels from the plasma membrane

Daniel A Nash, Henry G. Barrow, Robin Antrobus, Alex S. Nicholson, John Suberu, Harvey E. Johnston, Martin Potts, Marta A. Almeida, Valeria Lulla, Colin M. Crump, Anton James Enright, Michael P. Weekes, Janet Elwyn Deane, Stephen C. Graham

This study identifies HSV-1 protein pUL56 as responsible for removing voltage-gated ion channels from neuronal plasma membranes, disrupting calcium signaling and neuronal activity.

Science Advances · Oct 7, 2026Peer-reviewedMicrobiology

Sialylated Gangliosides are Required for Plasma Membrane Organization and Neuronal Function

Henry G. Barrow, Zhuang Zhuang Han, Alex S. Nicholson, Sinead Strasser, Daniel A Nash, John Suberu, Robin Antrobus, Daniëlle te Vruchte, David A. Priestman, Stephen C. Graham, Frances M. Platt, Janet Elwyn Deane

The paper shows that sialylated gangliosides are essential for plasma membrane organization and neuronal function, with ST3GAL5 deficiency causing severe disruptions in glycosphingolipid composition and neuronal activity.

bioRxiv · Apr 16, 2026 · PreprintCell Biology

Flexibility and modulation of translation initiation in enterovirus genomes

Rhian L. O’Connor, Georgia M. Cook, Jacqueline Hankinson, Ksenia V. Fominykh, Samantha H. Cheng, Daniel A Nash, Aurélie Cenier, Komal Nayak, Stephen C. Graham, Janet Elwyn Deane, Matthias Zilbauer, Andrew E. Firth, Valeria Lulla

This study shows enteroviruses can use two upstream AUGs for translation initiation, with the second AUG providing a competitive advantage in specific host environments.

PLoS Pathogens · Feb 9, 2026Peer-reviewedMicrobiology

Optimisation of lytic herpes simplex virus infection in human induced pluripotent stem cell derived cortical neurones

Daniel A Nash, Alex S. Nicholson, Henry G. Barrow, Viv Connor, Colin M. Crump, Janet Elwyn Deane, Stephen C. Graham

This study optimizes HSV-1 infection in human iPSC-derived cortical neurones, enabling efficient and synchronous infection for microscopy and biochemical analysis.

bioRxiv · Aug 22, 2025 · PreprintMicrobiology