Author

Elizabeth Breton

Van Andel InstituteORCID 0000-0001-9968-1878Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Lindsay K. MeyerdirkiD· 2 shared Michael X. HendersoniD· 2 shared Alysa KaseniD· 1 shared Ariel LouwrieriD· 1 shared Christine IsaguirreiD· 1 shared Colt D. CapaniD· 1 shared Daniella DeWeerdiD· 1 shared Danielle S. BassettiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Lindsay K. MeyerdirkORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedOct 17, 2025

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

Alysa Kasen, Sofia Lövestam, Elizabeth Breton…·Michael X. Henderson

This study shows that tau filament seeding capacity depends on both core structure and phosphorylation in the fuzzy coat, with phospho-mimetic residues restoring activity in modified tau.

12 citationstop 2%

protein structureexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 22, 2024

Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability

Naman Vatsa, Julia K. Brynildsen, Thomas M. Goralski…·Michael X. Henderson

The paper identifies group II p21-activated kinases as regulators of α-synucleinopathy by linking network vulnerability analysis to gene expression and pharmacological interventions.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky