Anatol C. Kreitzer

This study shows that dopamine neuron responses to food and water cues are modulated by internal state, with hunger-specific amplification of food cue responses.

This study shows that chronic hyperactivation of midbrain dopamine neurons leads to their preferential degeneration, suggesting increased neural activity may contribute to Parkinson's disease pathology.

This study shows that dysfunction in the dorsal intercalated nuclei of the amygdala (ITCd) in Sapap3-null mice leads to impaired extinction of avoidant behavior, which can be rescued by optogenetic inhibition of ITCd.

This study identifies fronto-striatal projections as regulators of approach-avoidance conflict, showing they control anxious avoidance behavior distinct from the dmPFC-amygdala circuit.

This study identifies a monosynaptic connection from the central amygdala to the mesencephalic locomotor region that suppresses locomotion during defensive behaviors in mice.

This paper introduces an open-source, cost-effective system for controlling optical components in intracranial photometry and processing signals from deep-brain structures in freely moving mice.

This paper develops GRABDA sensors to measure dopamine with high precision in multiple organisms during complex behaviors.

The paper shows that during adaptive learning, dMSNs and iMSNs in the striatum encode value information oppositely and reflect movement, motivation, and value information for decision-making.